Chemical Composition of the Cell Wall of Coccidioides immitis

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Polysaccharide of Coccidioides immitis.

Pappagianis, D. (University of California, Berkeley), E. W. Putman, and G. S. Kobayashi. Polysaccharide of Coccidioides immitis. J. Bacteriol. 82:714-723. 1961.-Soluble polysaccharide from mycelia or culture filtrates of Coccidioides immitis was found to consist mainly of mannose, but also included small quantities of galactose and another reducing sugar. Isolation of the polysaccharide by etha...

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Collagenolytic activity of Coccidioides immitis.

Coccidioides immitis appears to be unable to digest particulate collagen when cultured on collagen-containing semisolid culture media. However, all C. immitis strains solubilized collagen when the fungus was grown in liquid suspension cultures. Moreover, sterile culture filtrates were collagenolytic in collagen-buffer-agar plate assays.

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Coccidioides immitis vaccine: potential of an alkali-soluble, water-soluble cell wall antigen.

C-ASWS-M, the alkali-soluble, water-soluble cell wall antigen of Coccidioides immitis mycelia, was evaluated for its vaccine potential in mice. Vaccination with 0.5-, 1.5-, or 3-mg doses of C-ASWS-M in complete Freund adjuvant provided a significant level of protection against intraperitoneal challenge with 1,500 arthroconidia (P < 0.0001 with each dose). Vaccination with 1 mg of C-ASWS-M prote...

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Metabolism of mannitol by Coccidioides immitis.

Lones, George W. (National Institute of Allergy and Infectious Diseases, U.S. Public Health Service, Bethesda, Md.), and Carl Peacock. Metabolism of mannitol by Coccidioides immitis. J. Bacteriol. 87:1114-1117. 1964.-Strain M-11 of Coccidioides immitis was found to utilize mannitol for growth in the mycelial form but not in the spherule form. Cell-free extracts of both forms, grown on glucose, ...

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Pathogenesis of Coccidioides immitis in monkeys.

Converse, J. L. (U. S. Army Chemical Corps, Fort Detrick, Frederick, Md.), E. P. Lowe, M. W. Castleberry, G. P. Blundell, and A. R. Besemer. Pathogenesis of Coccidioides immitis in monkeys. J. Bacteriol. 83:871-878. 1962.-Respiratory exposure to arthrospores from the submerged growth of Coccidioides immitis, strain Cash, in liquid medium resulted in similar pathogenesis in monkeys to that of st...

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ژورنال

عنوان ژورنال: Nature

سال: 1954

ISSN: 0028-0836,1476-4687

DOI: 10.1038/173829a0